As @fthomas says, you shouldn't keep the engine for the study (too many details that will prevent the meshing at the same time imposing a very very fine mesh and therefore a very very long study).
The motor must indeed be replaced by a remote ground.
If there is real interference, either they must be eliminated or they are logical (tight mounting for example) and therefore it is necessary to define "Tight Fit" contacts between the faces concerned.
If there are screws, replace them with connectors, pins or bolts to be even more precise and to be able to check the strength of these screws.
you have to replace the screws with bolt connectors... This allows the forces to be recovered in the bolts... shearing, bending... you won't get any of this if you model your screws....
For the engine, you can retrieve the moments of inertia of the engine, and enter the values in Remote Loading/Mass... You can find this function in the loads... right-click on the folder loading... The best way is to define a system of coordinates at the center of gravity and to enter the inertia values taken from the center of gravity... We can also enter the mass rather than the moments of inertia...
- add the load/mass by selecting the motor mounts on the gearbox
- position on the previously defined coordinate system (or value x, y, z if known)
- engine mass
And that's it for remote charging.
Otherwise for the reinforcements, here is my previous remark in pictures.
And if the reducer is not to be calculated (e.g. element cots), you might as well put it as a load too. We will always have the values for the fixing screws of the reducer on the flange.